Mucopolysaccharidosis

=**MUCOPOLYSACCHARIDOSIS**= =**By Ariana and Diego** **What it is**=

Mucopolysaccharidosis is due to a difficiency of an enzyme in the body. All types of mucopolysaccharidosis are inherited by recessive traits, with one exeption they are all autosomal (they are not sex linked). Boys and girls alike can have these diseases if they recieve two copies of the relevant gene from both parents one from each parent the risk for each subsequent child is 1 out of 4. All types of MPS are lysosma; storage diseases. They involve enzymes found within the cell in lysosomal, miniatue structures that are packets of degradative enzymes. In this respect, MPS is like all the other disorders of lysosomal storage such as Gaucher disease, Fabry disease and Pompe disease. The **Symptoms of Mucopolysaccharidosis** -Joint stiffness - Mental Deterioration - Progressive Deafness - Dwarfing  -Short Stature -Limitation of Motion - Enlarged Forehead - Enlarged Lips - Misaligned Teeth - Enlarged Tongue Signs of the server form are Joint stiffness, and the mental deterioration, dwarfing etc..A death usally occurs by the age of 15 years old. The symoptoms of the mild form include short stature. - ENLARGED BELLY [THIS IS A 4 YEAR OLD NORMAL BRAIN]on the left [THIS IS A BRAIN OF A 4 YEAR OLD WITH MUCOPOLYSACHARIDOSIS] on the right Severe form will result in death at age fifteen. The people who have this disorder usualy suffer from limitation of movement, short stature, and enlarged belly. Every day activities are limited especialy if you get mental deterioration. There is currently no cure for this disease. treatments include physical therapy to delay joint problems and removing of he tonsils and adenoids to help breathing. Also you can have surgery to remove extra cerebrul fluid and correct hernias.
 * Symptoms of sever MPS II include**
 * Symoptoms of mild MPS II iclude**
 * Effects Of Mucopolysacharidosis**
 * Treatment/prognosis**

THIS IS A PICTURE OF AN ENLARGED FOR HEAD WHEN A BABY IS BORN! =Work Citation= "Basic summary for mucopolysaccharidosis"2 __What is mucopolysaccharidosis2__ [|]5/8/07 At 9:30 AM "mucopolysaccharidosis definition-medical dictionary definitions of popular medical terms" __Definition of mucopolysaccharidosis__ [|] 5/14/07 9:30 AM "National institute of nuerological disorders and stroke(NINDS)__Is there any treatment__ 5/15/07 At 10:47 AM

1.**Is mucopolysaccharidosis autosomal or sex-linked.
 * Discussion questions
 * 2.**Is mucopolysaccharidosis carried on a recessive or dominant gene?
 * 3.**Name 3 symptoms of mucopolysaccharidosis.

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